Oxidation of aorta by hydroxyl radicals produces structural changes in arterial proteins like elastin and collagen. This in turn results in change in the mechanical response of aorta. In this paper, a thermodynamically consistent constitutive model is developed within the framework of mixture theory, to describe the changes in aorta and isolated elastin with oxidation. The model is then studied under uniaxial extension using experimental data from literature.
The Effect of Oxidation on the Mechanical Response of Isolated Elastin and Aorta
Manuscript received March 10, 2018; final manuscript received March 26, 2019; published online April 22, 2019. Assoc. Editor: Seungik Baek.
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Mythravaruni, P., and Ravindran, P. (April 22, 2019). "The Effect of Oxidation on the Mechanical Response of Isolated Elastin and Aorta." ASME. J Biomech Eng. June 2019; 141(6): 061002. https://doi.org/10.1115/1.4043355
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