... 03 2022 synovial fluid magnetic microparticles viscosity osteoarthritis National Institute of Arthritis and Musculoskeletal and Skin Diseases 10.13039/100000069 R01AR068424 Degradation of synovial fluid can occur in multiple joint diseases, including osteoarthritis...

...Eleftheria Michalaki; Zhanna Nepiyushchikh; Josephine M. Rudd; Fabrice C. Bernard; Anish Mukherjee; Jay M. McKinney; Thanh N. Doan; Nick J. Willett; J. Brandon Dixon The lymphatic system has been proposed to play a crucial role in preventing the development and progression of osteoarthritis (OA...

...Nolan M. Norton; Brandon Barnds; Terence E. McIff; E. Bruce Toby; Kenneth J. Fischer The basilar thumb joint is the joint second most commonly affected by osteoarthritis (OA) in the hand. Evaluation of dorsal subluxation of the thumb during a functional task such as key pinch could help assess OA...

...Chloe L. Chung; Denis J. DiAngelo; Douglas W. Powell; Max R. Paquette Patients who sustain irreversible cartilage damage or joint instability from ankle injuries are likely to develop ankle osteoarthritis (OA). A dynamic ankle orthosis (DAO) was recently designed with the intent to offload the foot...

... were reduced compared with an all-plastic UKA component. Analyzed parameters were similar for an EI and a metal-backed onlay, but the EI component had the advantage of minimal resection of the stiffest bone. osteoarthritis tibia unicompartmental knee tibial stress tibial strain Early...

... degenerative changes in whole joints will help to further elucidate the mechanical etiology of osteoarthritis. This work was supported by a Whitaker Foundation Research Grant and Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education...

... related to joint contact mechanics. References [1] Buckwalter , J. A. , Saltzman , C. , and Brown , T. , 2004 , “ The Impact of Osteoarthritis: Implications for Research ,” Clin. Orthop. Relat. Res. , ( 427 Suppl ), pp. S6 – S15 . [2] Lawrence , R. C. , Felson , D. T...

...Jason W. Wheeler; Pete B. Shull; Thor F. Besier The external knee adduction moment (KAM) measured during gait is an indicator of tibiofemoral joint osteoarthritis progression and various strategies have been proposed to lower it. Gait retraining has been shown to be an effective, noninvasive...

...Christopher E. Henderson; Jill S. Higginson; Peter J. Barrance Knee osteoarthritis (OA) detrimentally impacts the lives of millions of older Americans through pain and decreased functional ability. Unfortunately, the pathomechanics and associated deviations from joint homeostasis that OA patients...

...Mack G. Gardner-Morse; Nelson J. Tacy; Bruce D. Beynnon; Maria L. Roemhildt Alterations to joint tissues, including subchondral bone, occur with osteoarthritis. A microindentation technique was developed to determine the local compressive modulus of subchondral bone. This test, in conjunction...

... the rate of progression of medial compartment knee osteoarthritis. The results of this study demonstrated that a subtle weight bearing shift to the medial side of the foot during walking produced with an active feedback system reduced the first peak of the knee adduction moment. While verbal instruction...

... biological tissues biomechanics boundary-elements methods cellular biophysics deformation elasticity encapsulation finite element analysis optimisation Young's modulus osteoarthritis collagen proteoglycan aggrecan numerical model inverse problem Mow , V. C. , Ratcliffe...

...Seungbum Koo, PhD; Nicholas J. Giori, MD; Garry E. Gold, MD; Chris O. Dyrby; Thomas P. Andriacchi, PhD Cartilage morphology change is an important biomarker for the progression of osteoarthritis. The purpose of this study was to assess the accuracy of in vivo cartilage thickness measurements from...

... saturable absorption photolysis proteins diffusion photobleaching pericellular matrix articular cartilage FRAP collagen proteoglycan osteoarthritis Articular cartilage is the connective tissue that lines surfaces of bones in synovial joints. Cartilage disease, primarily in the form...

... phenomenon. PG is nonuniformly distributed throughout the depth direction, and its amount or distribution may change in the degenerated articular cartilage such as osteoarthritis. In this paper, we used a 50 MHz ultrasound system to study the depth-dependent strain of articular cartilage under the osmotic...

...Li Cao; Inchan Youn; Farshid Guilak; Lori A Setton The mechanical properties of articular cartilage serve as important measures of tissue function or degeneration, and are known to change significantly with osteoarthritis. Interest in small animal and mouse models of osteoarthritis has increased...

... boundary-elements methods biological techniques physiological models boundary integral equations Cartilage Osteoarthritis Cell Mechanics Chondrocyte Mechanotransduction Articular cartilage serves as the resilient load-bearing surface at the ends of long bones in diarthroidal joints...

... Division December 27, 1999; revised manuscript received February 6, 2000. Associate Technical Editor: R. Vanderby, Jr. 27 December 1999 06 February 2000 viscoelasticity physiological models cellular biophysics biorheology Cartilage Osteoarthritis Cell Mechanics Chondrocyte...