... 01 2021 22 08 2021 01 12 2021 atherosclerosis plaque X-ray scattering collagen fibrils degree of orientation Every year an estimated 17 million people worldwide die of cardiovascular disease, making it responsible for one-third of all deaths [ 1 ]. Atherosclerosis...

... 10 12 2020 fluid–structure interaction pulse wave imaging biomechanical modeling pulse wave velocity finite element modeling atherosclerosis Pulse wave imaging (PWI) is an ultrasound-based elastography method that allows indirect quantification of arterial stiffness, via...

...Ashish Saxena; Eddie Yin Kwee Ng; Tejas Canchi; Jun Jie Tee; Lip Koon Ng Carotid artery stenosis is a form of atherosclerosis, where thrombus formation restricts the passage of blood through the carotid artery leading to irreversible damage in the brain tissue. The presence of stenosis...

... finite element simulations modeling the hyperelastic behavior and resulting stress distribution. The arterial wall composition mimics vessels in atherosclerosis–a complex cardiovascular disease and one of the leading causes of death globally. We formulate the training data to predict the maximum von...

...) and may become a risk factor for atherosclerosis. Here we performed a systematic computational study to relate CT morphological parameters to abnormal WSS, which is a predisposing factor to the formation of atherosclerotic lesions. Several idealized left coronary artery (LCA) models were created...

.... atherosclerosis magnetic resonance imaging carotid MRI simulations peak cap stress finite element analysis Atherosclerosis is a chronic cardiovascular disease in which plaques cause focal vessel wall thickening at flow-disturbed regions such as the carotid bifurcation [ 1 ]. Rupture prone, vulnerable...

... be useful for further investigation of the mechanism of plaque rupture based on in vivo patient data. plaque rupture stress intensity factor fatigue atherosclerosis Atheromatous plaque rupture can often lead to stroke or heart attack, which is the leading cause of death and disability...

..., 2013; accepted manuscript posted January 18, 2013; published online February 7, 2013. Editor: Victor H. Barocas. 03 10 2012 06 01 2013 18 01 2013 Studies investigating the relation between the focal nature of atherosclerosis and hemodynamic factors are employing increasingly...

... to further validate our findings. intraplaque hemorrhage fluid-structure interactions magnetic resonance imaging plaque wall stress atherosclerosis vulnerability Acute cardiovascular syndromes are often associated with the rupture of atherosclerotic plaque and may occur without any warning...

...Alexey V. Kamenskiy; Jason N. MacTaggart; Iraklis I. Pipinos; Jai Bikhchandani; Yuris A. Dzenis Accurate characterization of carotid artery geometry is vital to our understanding of the pathogenesis of atherosclerosis. Three-dimensional computer reconstructions based on medical imaging are now...

... and circumferential shrinkage could considerably improve the accuracy of in vivo MRI-based computational stress/strain predictions. 14 07 2011 03 01 2012 24 01 2012 08 02 2012 09 02 2012 carotid artery atherosclerosis MRI Cine plaque rupture It is widely accepted...

... vessels haemodynamics internal stresses numerical analysis physiological models stents numerical modeling atherosclerosis stenting procedures coronary bifurcations final kissing balloon Coronary artery stents were first introduced in the 1980s and revolutionized the practice...

... 06 2011 biomechanics biomedical MRI blood vessels fracture stress-strain relations carotid artery atherosclerosis MRI plaque rupture fluid structure interaction In this paper we introduce a serial MRI-based predictive computational and statistical framework combining...

.../(SICI)1096-9896(199701)181:1<93::AID-PATH696>3.0.CO;2-H Corti , R. , Hutter , R. , Badimon , J. J. , and Fuster , V. , 2004 , “ Evolving Concepts in the Triad of Atherosclerosis, Inflammation and Thrombosis ,” J. Thromb. Thrombolysis 0929-5305 , 17 ( 1 ), pp. 35 – 44...

..., by the Intramural Research Program of the National Institute on Aging, NIH. D.A.S. also acknowledges the support of a Heart & Stroke Foundation Career Investigator Award. Ku , D. N. , Giddens , D. P. , Zarins , C. K. , and Glagov , S. , 1985 , “ Pulsatile Flow and Atherosclerosis...

... density, which can result in the disturbance of local blood shear stress and may potentially lead to the development of atherosclerosis ( 7 ). Therefore, this area of LAD is of particular interest in the present study. As atherosclerotic lesions progress and accumulate in the coronary arteries, the blood...

... significantly different from that ( 263.44 ± 116.72   kPa ) of group 1 ( p = 0.00532 ) . biomechanics biomedical MRI diseases fracture internal stresses carotid artery atherosclerosis vulnerable plaque stroke MRI plaque rupture fluid-structure interaction...

... look like their parents, some internal forms, such as vascular geometry, may also be inherited. In this study, the geometric features of the aortic arch showed similarities within each of two pure mouse strains. Therefore, the well documented familial linkage of atherosclerosis might be the result...

...Lucy M. O'Keeffe; Gordon Muir; Anna V. Piterina; Tim McGloughlin Atherosclerosis is consistently found in bifurcations and curved segments of the circulatory system, indicating disturbed hemodynamics may participate in disease development. In vivo and in vitro studies have shown that endothelial...

... haemodynamics image reconstruction medical image processing wall shear stress atherosclerosis hemodynamic wall parameter carotid bifurcation There is much evidence suggesting that initiation and progression of atherosclerotic disease is influenced by “disturbed flow” ( 1 ). Notwithstanding...