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Keywords: mechanical loading
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Journal Articles

Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration

Ellen T. Bloom, Lily M. Lin, Ryan C. Locke, Alyssa Giordani, Erin Krassan, John M. Peloquin, Karin Grävare Silbernagel, Justin Parreno, Michael H. Santare, Megan L. Killian, Dawn M. Elliott
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2023, 145(8): 081003.
Paper No: BIO-22-1305
https://doi.org/10.1115/1.4062523
Published Online: June 16, 2023
.... In summary, isolated overload induces multiscale degenerative structural and functional changes in plantaris tendon. 1 Corresponding author. 21 11 2022 02 05 2023 16 06 2023 tendon mechanical loading degeneration overload overuse MRI histology Tendon degeneration...
View Article titled, Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration
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Topics: Biological tissues, Imaging, Stress, Tendons, Scanning electron microscopy, Surgery, Magnetic resonance imaging, Ablation (Vaporization technology), Microscale devices, Cycles
Includes: Supplementary data
Journal Articles

3D Finite Element Analysis of Nutrient Distributions and Cell Viability in the Intervertebral Disc: Effects of Deformation and Degeneration

Alicia R. Jackson, Chun-Yuh C. Huang, Mark D. Brown, Wei Yong Gu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2011, 133(9): 091006.
https://doi.org/10.1115/1.4004944
Published Online: October 11, 2011
... mechanical loading conditions were also investigated: a reference (undeformed) case and a 10% static deformation case. In general, nutrient levels decreased moving away from the nutritional supply at the disc periphery. Minimum glucose levels were at the interface between the nucleus and annulus regions...
View Article titled, 3D Finite Element Analysis of Nutrient Distributions and Cell Viability in the Intervertebral Disc: Effects of Deformation and Degeneration
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Topics: Biological tissues, Deformation, Density, Disks, Finite element analysis, Glucose, Intervertebral discs, Compression, Annulus, Finite element model
Journal Articles

Parametric Finite Element Analysis of Physical Stimuli Resulting From Mechanical Stimulation of Tissue Engineered Cartilage

Omotunde M. Babalola, B.S., Lawrence J. Bonassar, Ph.D.
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2009, 131(6): 061014.
https://doi.org/10.1115/1.3128672
Published Online: May 11, 2009
... of chondrocyte seeded scaffolds, to inform the modeling of spatial patterns of physical stimuli present in mechanically stimulated constructs. The literature survey revealed a large variation in conditions used in mechanical loading studies, with a peak to peak strain of 10% (i.e., the maximum amount...
View Article titled, Parametric Finite Element Analysis of Physical Stimuli Resulting From Mechanical Stimulation of Tissue Engineered Cartilage
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Topics: Biological tissues, Cartilage, Finite element analysis, Fluids, Permeability, Tissue engineering, Finite element model, Materials properties, Compression, Pressure