Considering steady laminar incompressible flow in a triple bifurcation, which represents generations three to six of the human respiratory system, air flow fields and micron-particle transport have been simulated for several combinations of relatively high and low inlet Reynolds and Stokes numbers. While the upstream bifurcations are hardly affected by the third bifurcation, complex air and particle flow fields occur in the daughter tubes leading to the third dividers. Variations in Reynolds number, and Stokes number, cause locally changing vortical air flows as well as irregular particle motions. Preferential concentration of particles can be induced by the secondary vortical flow in the tubes when the inlet Reynolds number is high enough. The air and particle velocity profiles in the third daughter tubes are still quite different from those in the upstream tubes, which indicates that additional downstream effects are possible. This work may contribute to respiratory dose estimation in health risk assessment studies, as well as the analyses of drug aerosol delivery.
Skip Nav Destination
Article navigation
June 2001
Technical Papers
Flow Structure and Particle Transport in a Triple Bifurcation Airway Model1
Z. Zhang,
Z. Zhang
Center for Environmental Medicine and Lung Biology, The University of North Carolina, Chapel Hill, NC 27599
Search for other works by this author on:
C. Kleinstreuer,
C. Kleinstreuer
Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695-7910
Search for other works by this author on:
C. S. Kim
C. S. Kim
Human Studies Division, National Health and Environmental Effects Research Laboratory, U.S. EPA, Research Triangle Park, NC 27711
Search for other works by this author on:
Z. Zhang
Center for Environmental Medicine and Lung Biology, The University of North Carolina, Chapel Hill, NC 27599
C. Kleinstreuer
Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695-7910
C. S. Kim
Human Studies Division, National Health and Environmental Effects Research Laboratory, U.S. EPA, Research Triangle Park, NC 27711
Contributed by the Fluids Engineering Division for publication in the JOURNAL OF FLUIDS ENGINEERING. Manuscript received by the Fluids Engineering Division January 9, 2000; revised manuscript received December 27, 2000. Associate Editor: J. K. Eaton.
J. Fluids Eng. Jun 2001, 123(2): 320-330 (11 pages)
Published Online: December 27, 2000
Article history
Received:
January 9, 2000
Revised:
December 27, 2000
Citation
Zhang, Z., Kleinstreuer, C., and Kim, C. S. (December 27, 2000). "Flow Structure and Particle Transport in a Triple Bifurcation Airway Model." ASME. J. Fluids Eng. June 2001; 123(2): 320–330. https://doi.org/10.1115/1.1359525
Download citation file:
Get Email Alerts
Related Articles
Targeted Drug Aeroso Deposition Analysis for a Four-Generation Lung Airway Model With Hemispherical Tumors
J Biomech Eng (April,2003)
Convective Dispersion During Steady Flow in the Conducting Airways of the Human Lung
J Biomech Eng (February,2008)
Optimal Drug-Aerosol Delivery to Predetermined Lung Sites
J. Heat Transfer (January,2011)
Effects of Inertia and Gravity on Liquid Plug Splitting at a Bifurcation
J Biomech Eng (October,2006)
Related Proceedings Papers
Related Chapters
Multiphase Flow Simulations of Sediment Particles in Mixed-flow Pumps
Mixed-flow Pumps: Modeling, Simulation, and Measurements
Fans and Air Handling Systems
Thermal Management of Telecommunications Equipment
Numerical Simulation of Ship's Air Intake System and Selections of Salt Aerosol Sampling Points
International Conference on Mechanical and Electrical Technology, 3rd, (ICMET-China 2011), Volumes 1–3