The paper presents the results of an investigation on inlet air cooling systems based on cool thermal storage, applied to combined cycle power plants. Such systems provide a significant increase of electric energy production in the peak hours; the charge of the cool thermal storage is performed instead during the night time. The inlet air cooling system also allows the plant to reduce power output dependence on ambient conditions. A combined cycle power plant operating in the Italian scenario is the object of this investigation. Two different technologies for cool thermal storage have been considered: ice harvester and stratified chilled water. To evaluate the performance of the combined cycle under different operating conditions, inlet cooling systems have been simulated with an in-house developed computational code. An economical analysis has been then performed. Different plant location sites have been considered, with the purpose to weigh up the influence of climatic conditions. Finally, a parametric analysis has been carried out in order to investigate how a variation of the thermal storage size affects the combined cycle performances and the investment profitability. It was found that both cool thermal storage technologies considered perform similarly in terms of gross extra production of energy. Despite this, the ice harvester shows higher parasitic load due to chillers consumptions. Warmer climates of the plant site resulted in a greater increase in the amount of operational hours than power output augmentation; investment profitability is different as well. Results of parametric analysis showed how important the size of inlet cooling storage may be for economical results.