Based on the newly developed geometrical model of open-cell metal foam, pool boiling heat transfer in open-cell metal foam, considering thermal responses of foam skeletons, is investigated by the phase-change lattice Boltzmann method (LBM). Pool boiling patterns are obtained at different heat fluxes. The effects of pore density and foam thickness on bubble dynamics and pool boiling heat transfer are revealed. The results show that “bubble entrainment” promotes fluid mixing and bubble sliding inside metal foam. Based on force analysis, the sliding bubble is pinned on the heating surface and cannot lift off completely at high heat flux due to the increasing surface tension force. Pool boiling heat transfer coefficient decreases with increasing pore density and foam thickness due to high bubble escaping resistance.