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Keywords: medical disorders
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Journal Articles
Journal:
Journal of Medical Devices
Article Type: Technical Briefs
J. Med. Devices. December 2011, 5(4): 044501.
Published Online: November 7, 2011
... biomechanics bone brain medical disorders prosthetics osteoporosis fractures internal fixation screw peek locking element pull-out Scheme of a screw locking element and the device used for its insertion. H = handles, M = male part, F = female part, P = pivoting jaw, G = interchangeable...
Abstract
Plates and non-locked screws used in the treatment of osteoporotic bone fractures frequently become loose due to everyday mechanical demands. Currently, locking plates and screws are the gold standard treatment for these fractures. However, their use has several limitations and complications as they are technically demanding, and their cost is very expensive. To improve the fixation strength of traditional unlocked plate and screw constructs, we have developed a new fixation system based on a very old concept. The system consists of a screw locking element (SLE) manufactured from PEEK, which is attached to the end of the screw shaft once it has traversed both bone cortices. A specially designed tool is used to facilitate its attachment to the screw. This tool makes it possible for the screw to traverse an osteosynthesis plate or lockwasher as well as both bone cortices and to easily find the SLE, fixing it against the far cortex. We tested the pull-out strength of SLEs and compared the results with previously published data for human femoral cortex pull-out strength. Our laboratory tests demonstrate that the mean SLE pull-out strength was 3864 ± 47.61 N, while that observed for a human femoral diaphysis cortex was 4071.54 ± 1461.69 N. This difference was not significant (p > 0.05). This new system can easily be used with any type of osteosynthesis in osteoporotic or osteopenic bones, with the screws being placed on weakened areas of the bone (e.g., fissure lines, previous orifices, or thinned metaphyseal bone cortex), or to replace over-torqued screws. It is particularly suitable for veterinary trauma, where immediate weight-bearing protection after fracture treatment is nearly impossible.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Research Papers
J. Med. Devices. June 2011, 5(2): 021003.
Published Online: June 17, 2011
..., surface tension, gravity, and buoyancy forces 21 10 2010 18 02 2011 17 06 2011 17 06 2011 catheters drug delivery systems mass spectroscopy medical control systems medical disorders O’Grady , N. P. , Alexander...
Abstract
Intravenous catheterization is the most common invasive medical procedure today and is designed to introduce medication directly into the blood stream. Common practice is to administer medicine with one syringe, followed by a saline flush to clear the line of any residual medication. The risk of infection due to the introduction of bacteria in the catheter hub is increased with the number of times the hub is accessed. In addition, the two-step process adds millions of nursing hours per year and is prone to error. The goal of this effort was to design and test a dual-chamber syringe that could be reliably used for both dispensing medicine and the saline flush, and be produced at a low cost. The syringe has a novel dual-chamber design with a proximal chamber for medicine and a distal chamber that contains saline. The saline chamber has a fixed volume when the handle is locked into position, which allows the handle to control the variable volume of the medicine chamber. Between the two chambers is a plunger that surrounds the small channel (which is an extension of the distal chamber) that separates the saline from the medicine. When the distal chamber is unlocked, the handle controls the volume of the saline chamber. By this mechanism, the syringe is able inject the medicine followed by the saline flush with a single access to the catheter hub. The smooth operation of the device relies on a locking mechanism to control the rear plunger and volume of the distal saline chamber, and a bubble plug residing in the small channel between the chambers that prevents mixing of the medicine and saline fluids. The bubble plug is held in place by a balance of forces that depend on geometric variables and fluid properties. The chosen design prevents mixing of the two fluids during the operation of the device, which was experimentally validated with mass spectrometry. The dual-chamber syringe has successfully achieved the design goal of a single syringe for the two-step catheter procedure of dispensing medicine and a saline flush. This novel design will reduce the potential for catheter-based infection, medical errors, medical waste, and clinician time. Preliminary test results indicate that this innovation can significantly improve the safety and efficiency of catheter-based administration of medicine.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027536.
Published Online: June 15, 2011
...Rong Fan; Christopher Hobson; Ahmed Bayoumi; John Mayer; William Wagner; Michael S. Sacks 15 06 2011 15 06 2011 biomechanics biomedical materials deformation elasticity finite element analysis haemodynamics medical disorders paediatrics prosthetics surgery tissue...
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027536.
Published Online: June 15, 2011
...Ed Summers; Thomas Cervantes; Rachel Batzer; Julia Stark; Raymond Lewis 15 06 2011 15 06 2011 biomedical equipment cancer cooling kidney medical disorders surgery Over 58,000 patients suffer from renal cell carcinoma annually in the United States. Treatment for this...
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027537.
Published Online: June 15, 2011
...Ahmed Rabbi; Reza Fazel-Rezai 15 06 2011 15 06 2011 electroencephalography feature extraction fuzzy logic medical disorders medical signal detection neurophysiology We present a fuzzy rule-based system for epileptic seizure onset detection. Two features based on...
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027527.
Published Online: June 14, 2011
...Oliver Bandschapp; Charles Soule; Paul A. Iaizzo 14 06 2011 14 06 2011 biomechanics electromyography force measurement medical disorders neuromuscular stimulation proteins Myotonic dystrophy is a dominantly inherited disorder characterized by myotonia and delayed...
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027519.
Published Online: June 13, 2011
...Byung Hyune Choi; A. Reum Seo; Kil Hwan Kim; Byoung-Hyun Min Min; So Ra Park 13 06 2011 13 06 2011 biomedical ultrasonics cellular biophysics enzymes genetics medical disorders molecular biophysics radiation therapy surgery Low-intensity ultrasound (LIUS) is a...
Journal Articles
Austin Oehlerking, James D. Meredith, Ian C. Smith, Phillip M. Nadeau, Teresa Gomez, Zachary A. Trimble, David P. Mooney, David L. Trumper
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027511.
Published Online: June 9, 2011
... medical control systems medical disorders paediatrics patient treatment phototransistors pressure sensors This paper describes a magnetic, nonoperative device and control system designed to treat long-gap esophageal atresia (LEA). This congenital disorder occurs in approximately 100 newborn...
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027512.
Published Online: June 9, 2011
...Kalyani Nair; Martin Morris; Charles Corrie; Brian Del-Bene; Michelle Eastburn; Julian Lin 09 06 2011 09 06 2011 biological fluid dynamics biomedical equipment brain medical control systems medical disorders prosthetics pumps An overlying problem with shunting...
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027505.
Published Online: June 9, 2011
...Polina A. Segalova; Guanglei Xiong; K. T. Rao; Christopher K. Zarins; Charles A. Taylor 09 06 2011 09 06 2011 blood vessels computational fluid dynamics computerised tomography diagnostic radiography haemodynamics medical disorders prosthetics Computer modeling of...
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2011, 5(2): 027509.
Published Online: June 9, 2011
...Thomas Lipoma; Pablo Bello; Carson Darling; Matt T. Bianchi 09 06 2011 09 06 2011 capacitive sensors medical disorders medical signal processing patient diagnosis pneumodynamics sleep This paper presents a shirt embedded with simple capacitive sensors that accurately...
Journal Articles
Edmond H. M. Lou, Emma K. Brunton, Fraaz Kamal, Andreas Renggli, Kyle Kemp, Justin Lewicke, Dulai Sukhdeep, Joe M. Watt, John Andersen
Journal:
Journal of Medical Devices
Article Type: Technical Briefs
J. Med. Devices. June 2011, 5(2): 024501.
Published Online: May 31, 2011
... 31 05 2011 biomedical electronics data acquisition gait analysis kinematics low-power electronics medical disorders paediatrics Fox , A. , Deakin , S. , Pettigrew , G. , and Paton , R. , 2006 , “ Serial Casting in the Treatment of Idiopathic Toe-Walkers and...
Abstract
Clinical gait analysis is the accepted “gold standard” for evaluating an individual’s walking pattern. However, in certain conditions such as idiopathic toe walking (ITW), the degree of voluntary control that a subject may elicit upon their walking pattern in a gait laboratory may not truly reflect their gait during daily activities. Therefore, a battery-powered, wireless data acquisition system was developed to record daily walking patterns to assist in the assessment of treatment outcomes in this patient population. The device was developed to be small ( 30 × 50 × 12 mm 3 ) , light-weight (15 g), easy to install, reliable, and consumed little power. It could be mounted across the laces of the shoe, while forces and walking activities were recorded to investigate the percentage of toe walking during the assessment. Laboratory tests were performed and preliminary clinical trials at a gait laboratory were done on six normal gait walkers. These volunteers also try to walk on their toes to simulate the toe walking at the gait laboratory. The system was able to track the gait pattern and determine the percentage of toe walking relative to normal gait. Three boys and one girl were diagnosed with ITW then participated into this study. A total of 4 sets thirty-three 10 min data sessions (5.5 h) were collected outside the laboratory. The results showed that the test subjects walked on their toes 70 ± 4 % of the total walking time, which was higher than that they performed 64 ± 5 % at the gait laboratory. This preliminary study shows promising results that the system should be able to use for clinical assessment and evaluation of children with ITW.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Research Papers
J. Med. Devices. June 2010, 4(2): 021003.
Published Online: August 4, 2010
... haemodynamics medical disorders optimisation stents aneurysm stents flow diversion strut position optimization Srinivas , K. , Ohta , M. , Nakayama , T. , Obayashi , S. , and Yamaguchi , T. , 2008 , “ Studies on Design Optimization of Coronary Stents ,” ASME J. Med...
Abstract
This work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30–60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Research Papers
J. Med. Devices. March 2010, 4(1): 011004.
Published Online: March 26, 2010
.../00207179508921959 Sira-Ramirez , H. , and Agrawal , S. K. , 2004 , Differentially Flat Systems , Dekker , New York . biomedical equipment brain lifts medical disorders neurophysiology patient care patient rehabilitation safety devices HLPR chair prototypes 1 and 2. Graphics...
Abstract
The home lift, position, and rehabilitation (HLPR) chair has a unique design and novel capabilities when compared with conventional powered wheelchairs. In addition to mobility, it provides lift and can transfer patients. Even though medical devices are developing at a rapid pace today, an aspect that is often overlooked in these developments is adherence to “rider safety standards.” The contributions of this paper are threefold: (i) novel design of a lift and transfer system, (ii) experiments and results toward improved stability test designs that include HLPR-type devices to meet rider safety standards, and (iii) autonomous navigation and control based on nonlinear system theory of dynamic feedback linearization. Stability experimental results show promise for multipurpose patient mobility, lift, and transfer devices such as HLPR. A method for autonomous maneuvers was tested in simulation and experiments. We also expect the autonomous or semi-autonomous mobility mode of the vehicle to be useful for riders who have potential neural and cognitive impairments.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2009, 3(2): 027532.
Published Online: July 9, 2009
... diseases finite element analysis mechanical testing medical computing medical disorders neurophysiology orthopaedics prosthetics titanium alloys 2009 American Society of Mechanical Engineers ...
Abstract
Arthritis, degenerative disc disease, spinal stenosis, and other ailments lead to the deterioration of the facet joints of the spine, causing pain and immobility in patients. Dynamic stabilization and arthroplasty of the facet joints have advantages over traditional fusion methods by eliminating pain while maintaining normal mobility and function. In the present work, a novel dynamic stabilization spine implant design was developed using computational analysis, and the final design was fabricated and mechanically tested. A model of a fused L4–L5 Functional Spinal Unit (FSU) was developed using Pro/Engineer (PTC Corporation, Needham, MA). The model was imported into commercial finite element analysis software Ansys (Ansys Inc., Canonsburg, PA), and meshed with the material properties of bone, intervertebral disc, and titanium alloy. Physiological loads (600N axial load, 10 N-m moment) were applied to the model construct following the protocol developed by others. The model was subjected to flexion/extension, axial rotation, and lateral bending, and was validated with the results reported by Kim et al. The validated FSU was used as a base to design and evaluate novel spine implant designs, using finite element anlysis. A comparison of the flexion-extension curve of six designs and an intact spine was carried out. Range of motion of the new designs showed up to 4 degrees in flexion and extension, compared to less than one degree flexion/extension in a fused spine. The design that reproduced normal range of motion best was optimized, fabricated and prepared for mechanical testing. The finalized dynamic stabilization design with spring insert was implanted into a L4-L5 FSU sawbone (Pacific Research Laboratories, Vashon, WA) using Stryker Xia pedicle screws. The construct was potted using PMMA, and was subjected to flexion/extension, axial rotation, and lateral bending loads using MTS mechanical testing machine. The stiffness of the design was assessed and compared with computational analysis results.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2009, 3(2): 027520.
Published Online: July 8, 2009
... leg-propelled mode and so, a greater number of calories were being burned during this 6-minute test. 08 07 2009 biomechanics biomedical measurement distance measurement handicapped aids medical disorders wheelchairs 2009 American Society of Mechanical Engineers ...
Abstract
A first student project to put pedals on a wheelchair for exercise and propulsion was unsuccessful. The need remained and in June of 2005 the “Eureka” event occurred. Seeing a five-year-old on her training-wheel-equipped bicycle suggested that a fifth wheel could be added in the center between the wheelchair's two large rear wheels, and a mast supported by the fifth wheel's axle could extend forward to support a front axle and pedal set. A chain drive completed the propulsion system. There are no pedal-powered wheelchairs currently on the market. Around 2001 a product (EZChair) without retractable pedals was on the market but withdrawn. A team at the University of Buffalo invented and patented a pedal-powered wheelchair in 1993 (US Patent 5,242,179), but it was not commercialized. Also, a Japanese company designed and built a series of fifth-wheel wheelchair designs. Between 2006 and late 2008 we built many prototypes incorporating geometries that permitted retracting the pedal. For compactness a “Pedalong” with three telescoping tubes was built but it proved impossible to secure tightly. In the next design twin telescoping tubes passing above and to the rear of the rear axle provided the desired extension. A clamp at the front of the outer tube provided tightness of the assembly. In the Northwestern research program (see below), there was some success, but awkwardness in operation prevented commercialization. In October 2008 a major design change from a fifth wheel in the center to a powering of the two standard rear wheels was begun. This required a new chain path geometry and addition of a differential to the drive train. With the new design user control, arm-powering and braking through the rear wheels is retained, and chair stability is improved. Twelve individuals with chronic post-stroke hemiplegia ( > 6 months post-stroke event) participated in a study to examine the metabolic energy expended when participants performed a 6-minute walk test, a 6 minute leg-propelled wheelchair trial (using the Pedalong), and a 6 minute arm-propelled wheelchair trial. VO2, VCO2, and distance traveled were measured using a portable metablic cart system and wheel-based distance measurement system. The Pedalong and walking trials showed equivalent oxygen consumption levels, but manual pushing was, on average, significantly less. All three modes (walking, leg-propelled and arm-propelled) resulting in similar distances traveled within the 6 minute period. The leg-propelled trials generated the greatest amount of VCO2 during expiration compared with the other modes. This means that more of the available oxygen is being utilized (metabolized) during the leg-propelled mode and so, a greater number of calories were being burned during this 6-minute test.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2009, 3(2): 027522.
Published Online: July 8, 2009
... 07 2009 biomedical optical imaging electro-optical devices endoscopes fibre optic sensors medical disorders medical image processing neural nets optical scanners 2009 American Society of Mechanical Engineers ...
Abstract
Technological advancements in endoscopy design are in current development due to the increased demand for minimally invasive medical procedures. One such advancement is reducing the overall size of the endoscope system while maintaining the resolution and field-of-view (FOV). Reduction of size results in less tissue damage and trauma during operation as well as faster recovery times for patients. Additionally, areas that are inaccessible by today's endoscope designs will be possible to examine. Current endoscopes use either a bundle of optical fibers (optical waveguides) and/or one or more cameras having an array of detectors to capture an image. Thus, the diameter of these devices employed for remote imaging cannot be reduced to smaller than the image size. Even if one ignores additional optical fibers used for illumination of a region of interest, the scope diameter is therefore limited by the individual pixel size of a camera or by the diameter of optical fibers used to acquire the image. Therefore, it is apparent to achieve scopes with less than 3 mm overall diameter using current technologies, resolution and/or FOV must be sacrificed by having fewer pixel elements. All commercially available scopes suffer from this fundamental tradeoff between high image quality and small size. More recently, our research has been working on developing a 2-D electro-optic scanner potentially be implemented for clinical endoscopic imaging application. The proposed optical device has several unique advantages. Electro-optical scanning offers a sensitive, facile, accurate, and superb quality method to capture images of physical and biological tissues. In addition, the minute physical size of the imaging system has a much needed advantage over conventional imaging systems. The proposed design is based on the fact that the propagation direction of a light beam can be changed when the index of refraction of an electro-optic medium is altered by the application of an external electric field. The basic design of the system consists of a thin film electro-optic polymer waveguide with built-in cascaded prisms structure for horizontal beam deflection and an electro-optic grating structure for vertical beam deflection. The cascaded prisms are combined with the electro-optic polymer to create a voltage-controlled horizontal beam deflection. A grating coupler, a structure that is commonly used as light coupling device for dielectric waveguide, is combined with the EO polymer to create the vertical controlled beam deflection. A collimated light beam coupled into the waveguide by a mechanical coupler via an optical fiber cascaded down these two deflection stages. When the beam exits, the emitted light beam is displaced along two orthogonal directions in a raster pattern. A photodetector array integrated in the same substrate captured the reflected intensity. The scanned imaged is then analyzed and reconstruct based on the received signal.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2009, 3(2): 027514.
Published Online: July 7, 2009
... hospital setting and in the home, Acute Myocardial Infarction as well as Angina Pectoris. 07 07 2009 blood vessels cardiovascular system diseases haemodynamics medical disorders orthotics 2009 American Society of Mechanical Engineers ...
Abstract
The primary function of the ventricular chambers of the heart is to provide the proper volume of blood to the entire body that fulfills its energy requirements under a wide variety of normal and pathologic settings. If the ventricles are unable to perform this task properly, and the functions of the body deteriorates despite optimal medical management, mechanical methods are utilized to either complement or replace the pumping function of the cardiac ventricles. This presentation will describe the evolution of a non-invasive method of assisting the circulation called “counterpulsation,” and the current state of the development of an “External Left Ventricular Assist Device” (XLVAV). In this method, in the first part of the cardiac cycle, when the heart is relaxed, cardiac diastole, the device exerts a positive pressure external to the lower extremities. This increases coronary artery blood flow and cardiac output. Then when the ventricle contracts, cardiac systole, the device exerts a negative pressure, thus drawing blood away from the heart into the lower extremities, resulting in a reduction of the work and energy requirement of the left ventricle. Experimental and clinical data will be presented that describe the following successive stages of development: 1. The initial experience of Osborn in 1962 using a pressure suit and air actuation was tested in a canine model and in normal volunteers, but was not successful since sufficient pressure was not exerted on the vascular bed of the lower extremities. 2. The initial experimental experience of Birtwell and Soroff in a canine model in 1962 using water as the actuating medium. 3. The construction of a device by Birtwell with cuff-type actuators around the legs, thighs and buttocks that were inflated with water. The cuffs had rigid shells to allow pressure to be exerted to the limbs. The device was successful in increasing diastolic pressure and coronary blood flow and was used successfully in a multicenter study as an initial treatment of patients with acute myocardial infarctions. However, since the device could only apply positive pressure, it could not be used to reduce systolic pressure. 4. The device was then modified to also apply negative pressure during cardiac systole, a major step forward, and tested in a multicenter study in patients with cardiogenic shock following myocardial infacrtions with an impressive increase in the survival rate from 15% to 45%. However, the device presented logistical and patient movement problems. 5. The next evolution in the device design was the use of air to inflate the actuator cuffs. This represented a significant breakthrough, and has been successfully used in the treatment of angina pectoris by increasing coronary blood flow and the promotion or creation of collateral circulation in the myocardium. The serious shortcoming of this device is that is cannot produce negative pressure during cardiac systole, i.e., the only means of assisting the left ventricle in patients with Congestive Heart Failure. 6. The device to be described can apply negative as well as positive pressure to the lower extremities using air as the actuating medium. The device is mobile and compact, and should be effective in the treatment of patients with Congestive Heart Failure both in the hospital setting and in the home, Acute Myocardial Infarction as well as Angina Pectoris.
Journal Articles
Journal:
Journal of Medical Devices
Article Type: Design Of Medical Devices Conference Abstracts
J. Med. Devices. June 2009, 3(2): 027503.
Published Online: June 29, 2009
.... 29 06 2009 biomechanics electromyography medical disorders orthopaedics orthotics patient rehabilitation user interfaces virtual instrumentation 2009 American Society of Mechanical Engineers ...
Abstract
Objective: To design a ‘smart’ leg press machine that improves upon current rehabilitative practices for degenerative knee disorders such as osteoarthritis as well as injury induced knee pathologies. As its design entails, the machine provides rehabilitative assistance through strength training of upper leg muscles, with focus on the vastus medialis and vastus lateralis of the quadriceps group. The Therapress is designed to further improve the rate and quality of joint rehabilitation. The TP1600i is unique to current physical therapy practices because it incorporates three documented and proven strategies to combat quadriceps weakness: strength training, electrotherapy, and biofeedback [1,2]. The machine is designed to aid the user in regaining lost quadriceps strength, a condition indicative of poor knee health [3]. The machine incorporates a novel package of biofeedback, automated continuous variable resistance, and progress assessment, while maintaining subject specificity. The Therapress system utilizes a LabVIEW interface, which acquires and processes physiological signals recorded from the subject, as well as serves as a controller for output. These signals include surface electromyography (EMG) of the quadriceps, reaction forces at the foot (an indirect measurement of exercise resistance), and knee range of motion (ROM). Additionally, the subject is outfitted with stimulatory electrodes which function to characterize muscle recruitment using the Central Activation Ratio (CAR), as well as to therapeutically excite the muscle and induce accelerated hypertrophy [4]. Automated continuous variable resistance is achieved through a resistive hydraulic cylinder, which utilizes a servo motor to change the orifice size of partially overlapping valves during and between exercise sets. The resistance is adjusted based on user input of exertion and pain levels into the LabVIEW interface. The footplate of the machine houses four force sensing units to measure the resistance offered by the cylinder. A biofeedback arm attached to the system provides the subject with real-time data of their performance, including integrated EMG activity, ROM, and force production. Inclusion of biofeedback in quadriceps exercise regimens has been shown to increase strength gain [2]. The design allows the user to be in control of the exercise intensity at all times, while the machine works to maximize the efficacy of the protocol. The TP1600i is designed as a cost effective and time efficient alternative for the rehabilitation of debilitating knee disorders in a physical therapy protocol, and its ease of operation may qualify it for home use as well.