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Francis Loth
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Journal Articles

The Relationship Between Imbalance Symptom and Cardiac Pulsation Induced Mechanical Strain in the Brainstem and Cerebellum for Chiari Malformation Type I

Mohamad Motaz F. Al Samman, Alaaddin Ibrahimy, Blaise Simplice Talla Nwotchouang, John N. Oshinski, Daniel L. Barrow, Philip A. Allen, Rouzbeh Amini, Rafeeque A. Bhadelia, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2023, 145(8): 081005.
Paper No: BIO-23-1003
https://doi.org/10.1115/1.4062723
Published Online: June 21, 2023
View Article titled, The Relationship Between Imbalance Symptom and Cardiac Pulsation Induced Mechanical Strain in the Brainstem and Cerebellum for Chiari Malformation Type I
Open the PDF for The Relationship Between Imbalance Symptom and Cardiac Pulsation Induced Mechanical Strain in the Brainstem and Cerebellum for Chiari Malformation Type I in another window
Topics: Biological tissues, Cardiac cycle, Damage, Displacement, Magnetic resonance imaging, Rotation, Spinal cord, Biomechanics, Encryption, Nervous system
Journal Articles

Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis

Rayanne Pinto Costa, Blaise Simplice Talla Nwotchouang, Junyao Yao, Dipankar Biswas, David Casey, Ruel McKenzie, Frederick Sebastian, Rouzbeh Amini, David A. Steinman, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2023, 145(4): 041001.
Paper No: BIO-21-1404
https://doi.org/10.1115/1.4055856
Published Online: December 5, 2022
View Article titled, Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis
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Topics: Blood, Flow (Dynamics), Reynolds number, Rheology, Turbulence, Vibration, Water, Fluids, Pipes, Laser Doppler vibrometers
Proceedings Papers

Numerical Simulation of Pulsatile Flow Inside an End-to-Side Vascular Graft

Francis Loth, Kai Kang, Ming Lei
Proc. ASME. IMECE98, Advances in Bioengineering, 79-80, November 15–20, 1998
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1998-0039
https://doi.org/10.1115/IMECE1998-0039
View Paper titled, Numerical Simulation of Pulsatile Flow Inside an End-to-Side Vascular Graft
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Topics: Computer simulation, Pulsatile flow, Flow (Dynamics), Geometry, Shear stress
Proceedings Papers

Hydrodynamic Modeling of Cerebrospinal Fluid Motion Within the Spinal Cavity

M. Atif Yardimci, Francis Loth, Noam Alperin
Proc. ASME. IMECE2000, Advances in Bioengineering, 291-292, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2625
https://doi.org/10.1115/IMECE2000-2625
View Paper titled, Hydrodynamic Modeling of Cerebrospinal Fluid Motion Within the Spinal Cavity
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Topics: Canals, Cavities, Cerebrospinal fluid, Computer simulation, Flow (Dynamics), Geometry, Modeling, Pressure gradient, Shear stress, Spinal cord
Proceedings Papers

Comparison of Experimental and Numerical Simulations of Flow Within an Arterio-Venous Graft

Paul F. Fischer, Seung Lee, Francis Loth, Hisham S. Bassiouny, Nurullah Arslan
Proc. ASME. IMECE2000, Advances in Bioengineering, 275-276, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2617
https://doi.org/10.1115/IMECE2000-2617
View Paper titled, Comparison of Experimental and Numerical Simulations of Flow Within an Arterio-Venous Graft
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Topics: Computer simulation, Flow (Dynamics), Turbulence, Bifurcation, Computation, Computational fluid dynamics, Fluid dynamics, Laser Doppler anemometry, Reynolds number
Journal Articles

Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions

Rayanne Pinto Costa, Blaise Simplice Talla Nwotchouang, Junyao Yao, Dipankar Biswas, David Casey, Ruel McKenzie, David A. Steinman, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2022, 144(3): 031008.
Paper No: BIO-21-1111
https://doi.org/10.1115/1.4052370
Published Online: October 14, 2021
View Article titled, Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions
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Topics: Blood, Flow (Dynamics), Fluids, Reynolds number, Turbulence, Viscosity, Water, Rheology, Pipes, Shear rate
Journal Articles

Association Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I

Alaaddin Ibrahimy, Chi-Wen Christina Huang, Abraham F. Bezuidenhout, Philip A. Allen, Rafeeque A. Bhadelia, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2021, 143(5): 051003.
Paper No: BIO-20-1201
https://doi.org/10.1115/1.4049788
Published Online: March 4, 2021
View Article titled, Association Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I
Open the PDF for Association Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I in another window
Topics: Cerebrospinal fluid, Computational fluid dynamics, Flow (Dynamics), Canals, Magnetic resonance imaging
Journal Articles

Regional Quantification of Brain Tissue Strain Using Displacement-Encoding With Stimulated Echoes Magnetic Resonance Imaging

Soroush Heidari Pahlavian, John Oshinski, Xiaodong Zhong, Francis Loth, Rouzbeh Amini
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2018, 140(8): 081010.
Paper No: BIO-17-1563
https://doi.org/10.1115/1.4040227
Published Online: June 15, 2018
View Article titled, Regional Quantification of Brain Tissue Strain Using Displacement-Encoding With Stimulated Echoes Magnetic Resonance Imaging
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Topics: Biological tissues, Brain, Displacement, Magnetic resonance imaging, Encryption
Journal Articles

Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts

Keyvan Amini Khoiy, Dipankar Biswas, Thomas N. Decker, Kourosh T. Asgarian, Francis Loth, Rouzbeh Amini
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2016, 138(11): 111006.
Paper No: BIO-16-1216
https://doi.org/10.1115/1.4034621
Published Online: October 21, 2016
View Article titled, Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts
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Topics: Deformation, Pressure, Valves, Pulmonary artery, Annulus, Pumps, Flow (Dynamics), Errors
Includes: Supplementary data
Journal Articles

Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions

Dipankar Biswas, David M. Casey, Douglas C. Crowder, David A. Steinman, Yang H. Yun, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2016, 138(7): 071001.
Paper No: BIO-14-1507
https://doi.org/10.1115/1.4033474
Published Online: June 7, 2016
View Article titled, Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions
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Topics: Blood, Flow (Dynamics), Fluids, Pipes, Viscosity, Rheology, Turbulence
Journal Articles

Characterization of the Discrepancies Between Four-Dimensional Phase-Contrast Magnetic Resonance Imaging and In-Silico Simulations of Cerebrospinal Fluid Dynamics

Soroush Heidari Pahlavian, Alexander C. Bunck, Francis Loth, R. Shane Tubbs, Theresia Yiallourou, Jan Robert Kroeger, Walter Heindel, Bryn A. Martin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2015, 137(5): 051002.
Paper No: BIO-14-1406
https://doi.org/10.1115/1.4029699
Published Online: May 1, 2015
View Article titled, Characterization of the Discrepancies Between Four-Dimensional Phase-Contrast Magnetic Resonance Imaging and In-Silico Simulations of Cerebrospinal Fluid Dynamics
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Topics: Computational fluid dynamics, Flow (Dynamics), Simulation, Magnetic resonance imaging
Includes: Supplementary data
Proceedings Papers

MR Measurement of Pulse Wave Velocity in the Spinal Canal

Bryn A. Martin, Francis Loth, Wojciech Kalata, John N. Oshinski
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 793-794, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193082
https://doi.org/10.1115/SBC2008-193082
View Paper titled, MR Measurement of Pulse Wave Velocity in the Spinal Canal
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Topics: Canals, Waves, Velocity measurement, Cardiac cycle, Cerebrospinal fluid, Diseases, Pressure, Resolution (Optics)
Journal Articles

Cerebrospinal Fluid Flow Impedance is Elevated in Type I Chiari Malformation

Nicholas Shaffer, Bryn A. Martin, Brandon Rocque, Casey Madura, Oliver Wieben, Bermans J. Iskandar, Stephen Dombrowski, Mark Luciano, John N. Oshinski, Francis Loth
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021012.
Paper No: BIO-13-1402
https://doi.org/10.1115/1.4026316
Published Online: February 5, 2014
View Article titled, Cerebrospinal Fluid Flow Impedance is Elevated in Type I Chiari Malformation
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Topics: Cerebrospinal fluid, Computational fluid dynamics, Flow (Dynamics), Magnetic resonance imaging, Modeling, Boundary-value problems, Anatomy, Biomechanics, Simulation, Statistical analysis
Proceedings Papers

Relation of Cerebrospinal Fluid Flow Impedance and Cerebellar Herniation in Type I Chiari Malformation

Nicholas Shaffer, Bryn Martin, Brandon Rocque, Casey Madura, Bermans Iskandar, Oliver Wieben, Stephen Dombrowski, Mark Luciano, John Oshinski, Francis Loth
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT46A006, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14808
https://doi.org/10.1115/SBC2013-14808
View Paper titled, Relation of Cerebrospinal Fluid Flow Impedance and Cerebellar Herniation in Type I Chiari Malformation
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Topics: Cerebrospinal fluid, Flow (Dynamics)
Proceedings Papers

The Influence of Coughing on Cerebrospinal Fluid Pressure in an In Vitro Syringomyelia Model With Spinal Canal Stenosis

Bryn A. Martin, Francis Loth
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 893-894, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206784
https://doi.org/10.1115/SBC2009-206784
View Paper titled, The Influence of Coughing on Cerebrospinal Fluid Pressure in an In Vitro Syringomyelia Model With Spinal Canal Stenosis
Open the PDF for The Influence of Coughing on Cerebrospinal Fluid Pressure in an In Vitro Syringomyelia Model With Spinal Canal Stenosis in another window
Topics: Biomechanics, Canals, Cerebrospinal fluid, Pressure
Proceedings Papers

Fluid Dynamic Analysis of Upper Airway of an Obstructive Sleep Apnea Patient Pre and Post Surgery

Dipankar Biswas, Francis Loth, Matthew L. Krauza, Rachael J. Pohle-Krauza, Adrian G. Dan, John G. Zografakis
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1203-1204, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80726
https://doi.org/10.1115/SBC2012-80726
View Paper titled, Fluid Dynamic Analysis of Upper Airway of an Obstructive Sleep Apnea Patient Pre and Post Surgery
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Topics: Computational fluid dynamics, Dynamic analysis, Fluids, Sleep, Surgery
Proceedings Papers

Pathological Biomechanics of Cerebrospinal Fluid Pressure in Syringomyelia: Fluid Structure Interaction of an In Vitro Coaxial Elastic Tube System

Bryn A. Martin, Richard Labuda, Thomas J. Royston, John N. Oshinski, Bermans Iskandar, Francis Loth
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 941-942, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204685
https://doi.org/10.1115/SBC2009-204685
View Paper titled, Pathological Biomechanics of Cerebrospinal Fluid Pressure in Syringomyelia: Fluid Structure Interaction of an In Vitro Coaxial Elastic Tube System
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Topics: Biomechanics, Cerebrospinal fluid, Fluid structure interaction, Pressure, Spinal cord
Proceedings Papers

CFD Challenge: Experimental Benchmarking Data for the Pressure Drop Across a Cerebral Aneurysm Model

Paul Fahy, Michael Walsh, Francis Loth, Florentina Ene, Patrick Delassus, Liam Morris
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 129-130, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80442
https://doi.org/10.1115/SBC2012-80442
View Paper titled, CFD Challenge: Experimental Benchmarking Data for the Pressure Drop Across a Cerebral Aneurysm Model
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Topics: Aneurysms, Aorta, Biomedical imaging, Biomedicine, Computational fluid dynamics, Diseases, Flow (Dynamics), Physiology, Pressure drop, Testing
Proceedings Papers

CFD Challenge: Modeling Blood Flow Dynamics in a Cerebral Aneurysm Using Fluent

Nicholas Shaffer, Francis Loth
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 157-158, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80877
https://doi.org/10.1115/SBC2012-80877
View Paper titled, CFD Challenge: Modeling Blood Flow Dynamics in a Cerebral Aneurysm Using Fluent
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Topics: Aneurysms, Blood flow, Computational fluid dynamics, Dynamics (Mechanics), Modeling, Air flow, Cardiovascular system, Cerebrospinal fluid, Flow (Dynamics), Physiology
Proceedings Papers

Flow System to Detect Transitional Flow Based on Pulsed Doppler Ultrasound Velocity Profiles

Narender Ambati, Dipankar Biswas, Francis Loth, Stanley E. Rittgers, Steven A. Jones
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 967-968, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80801
https://doi.org/10.1115/SBC2012-80801
View Paper titled, Flow System to Detect Transitional Flow Based on Pulsed Doppler Ultrasound Velocity Profiles
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Topics: Flow (Dynamics), Ultrasound, Fluids, Reynolds number, Turbulence, Water, Blood, Blood flow, Circuits, Pipes